SEMESTER LEARNING PLAN
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Course Title: Traditional Medicinal Chemistry (KOT)
MK code: AKM21 449
Credit Weight: 2
Group of Courts: Elective
Semester: 5
Prerequisite Course: –
Lecturer:
Dr. Meiny Suzery, M.Si
Dr. Bambang Cahyono
Graduate Learning Outcomes (GLO)
| Attitude | GLO1-(S9) | Demonstrate an attitude of responsibility for work in their field of expertise independently. |
| Knowledge | GLO2-(PP2) | Mastering complete operational knowledge of functions, how to operate standard chemical instruments, as well as data and information analysis of the instrument |
| General Skills | GLO3 -(KU1) | Able to apply logical, critical, systematic, and innovative thinking in the context of the development or implementation of science and technology that pays attention to and uses humanities values by their field of expertise |
| GLO4 -(KU2) | Able to demonstrate independent, quality, and measurable performance |
Course Description
| Week | Expected ability (Sub-CLO) | Study Materials/ Learning Materials | Learning methods | Student Learning Experience | Time (minutes) | Evaluation | |
| Criteria and Indicators | % | ||||||
| 1 | Able to explain several aspects related to the scope of chemistry in the development of traditional medicine, applicable regulations and development roadmaps (C2, P2, A3) | Traditional Medicine Development Pattern
• Definition and History of Traditional Medicine Development • Roadmap for traditional medicine development (from upstream to downstream) • Several regulations related to traditional medicine in Indonesia |
Discovery learning
Cooperative learning |
Lecture,
question and answer |
FF : 2 x (1 x 50 min);
SS: 1 x (2 x 60 min); ST: 1 x (2 x 60 min) |
accuracy in argument | |
| 2 | Able to show the uniqueness of organic molecules in plant materials that are related to taxa (C2, A3) | Bioactive Compounds commonly found in traditional medicinal raw materials (Part-1)
The difference between secondary and primary metabolism and the mechanism by which these materials are formed Characteristics of the structure of monoterpenes, diterpenes, triterpenes, flavonoids (phenolics) and alkaloids |
Discovery learning
Cooperative learning |
Lecture,
question and answer |
FF : 2 x (1 x 50 min);
SS: 1 x (2 x 60 min); ST: 1 x (2 x 60 min) |
accuracy in argument | |
| 3 | Able to show the uniqueness of organic molecules in plant materials that are related to taxa (C2, A3) | Bioactive Compounds commonly found in traditional medicinal raw materials (Part-2)
Chemotaxonomy in traditional medicine Rapid test for the presence of bioactive compounds in plants |
Discovery learning
Cooperative learning Problem Based Learning |
Lecture,
question and answer |
FF : 2 x (1 x 50 min);
SS: 1 x (2 x 60 min); ST: 1 x (2 x 60 min) |
accuracy in argument | |
| 4 | Able to explain how to test, benefit and safety of traditional medicine (C2, A3) | From in vitro trials to clinical trials, what should be done? (part 1)
• Evidence base in traditional medicine • Some examples of in vitro tests |
Discovery learning
Cooperative learning Problem Based Learning |
Lecture,
question and answer |
FF : 2 x (1 x 50 min);
SS: 1 x (2 x 60 min); ST: 1 x (2 x 60 min) |
accuracy in argument | |
| 5 | Able to explain how to test, benefit and safety of traditional medicine (C2, A3) | From in vitro trials to clinical trials, what should be done? (part-2)
• Preclinical trials, Toxicity (safety) tests and Clinical trials • How to provide extracts of test materials and convert preclinical to clinical preparations |
Discovery learning
Cooperative learning Problem Based Learning |
Lecture,
question and answer |
FF : 2 x (1 x 50 min);
SS: 1 x (2 x 60 min); ST: 1 x (2 x 60 min) |
accuracy in argument | |
| 6 | able to choose the right method for the purposes of analysis (standardization) of traditional medicine based on the content of bioactive compounds (C3, A3), | Standardization of Traditional Medicine (Part-1)
Several standards for traditional medicinal commodities (SNI, Indonesian Herbal Pharmacopoeia, other Minister of Health Regulations) Several methods and examples of the results of the physical (organoleptic) analysis |
Discovery learning
Cooperative learning Problem Based Learning |
Lecture,
question and answer |
FF : 2 x (1 x 50 min);
SS: 1 x (2 x 60 min); ST: 1 x (2 x 60 min) |
accuracy in argument | |
| 7 | Sub Competency-4
able to choose the right method for the purposes of analysis (standardization) of traditional medicine based on the content of bioactive compounds (C3, A3), |
Standardization of Traditional Medicine (Part-2)
Some examples and results of chemical analysis Some examples and results of microbiological analysis How to Validate the test method |
Discovery learning
Cooperative learning Problem Based Learning |
Lecture,
question and answer |
FF : 2 x (1 x 50 min);
SS: 1 x (2 x 60 min); ST: 1 x (2 x 60 min) |
accuracy in argument | |
|
8
|
|
Midterm exam | Written exam | 90 | The truth and completeness of the answer to the question | ||
| 9 | Students are able to explain the mechanism of action of traditional medicinal ingredients based on the content of their bioactive compounds (C2, A3) | Enzymatic mechanism: relation of chemical structure in healing/inhibition of selected diseases (Part-1)
Examples of the mechanism of tumor development and natural bioactive compounds that can inhibit its development An example of the mechanism of increasing cholesterol levels (hypoglycemia) and its healing mechanism through the use of natural bioactive compounds |
Discovery learning
Cooperative learning Problem Based Learning |
Lecture,
question and answer |
FF : 1 x (1 x 50 min);
SS: 1 x (1 x 60 min); ST: 1 x (1 x 60 min) |
accuracy in argument | |
| 10 | Students are able to explain the mechanism of action of traditional medicinal ingredients based on the content of their bioactive compounds (C2, A3) | Enzymatic mechanisms: chemical structure relationships in the cure/inhibition of selected diseases (Part-2)
An example of the mechanism of increasing cholesterol levels (hypoglycemia) and its healing mechanism through the use of natural bioactive compounds |
Discovery learning
Cooperative learning Problem Based Learning |
Lecture,
question and answer |
FF : 1 x (1 x 50 min);
SS: 1 x (1 x 60 min); ST: 1 x (1 x 60 min) |
accuracy in argument | |
| 11 | Students are able to determine the right dose of traditional medicinal ingredients selected based on formulas and clinical or preclinical trial research in the literature (C3, A3) | Extraction, dosage calculation and formulation of traditional medicine (Part-1)
• Various ways of preparing extract • Conversion from animal to human and vice versa |
Discovery learning
Cooperative learning Problem Based Learning |
Lecture,
question and answer |
FF : 2 x (1 x 50 min);
SS: 1 x (2 x 60 min); ST: 1 x (2 x 60 min) |
accuracy in argument | |
| 12 | Students are able to determine the right dose of traditional medicinal ingredients selected based on formulas and clinical or preclinical trial research in the literature (C3, A3) | Extraction, dosage calculation and formulation of traditional medicine (Part-2)
• Traditional medicine formulas: introduction to ingredients and their selection |
Discovery learning
Cooperative learning Problem Based Learning |
Lecture,
question and answer |
FF : 2 x (1 x 50 min);
SS: 1 x (2 x 60 min); ST: 1 x (2 x 60 min) |
accuracy in argument | |
| 13 | Students are able to design a new traditional medicine formula (after combining the elements of bioactive compound content and the alleged mechanism for curing certain diseases, through a project that is systematically designed) and the alleged mechanism for the cure of certain diseases, through a project that is systematically designed and presented. with quality and measurable performance (C6, A3, P3) | Student inventions (Part-1)
New Formula of Traditional Medicine |
Discovery learning
Cooperative learning Problem Based Learning |
Lecture,
question and answer |
FF : 2 x (1 x 50 min);
SS: 1 x (2 x 60 min); ST: 1 x (2 x 60 min) |
accuracy in argument | |
| 14 | Students are able to design a new traditional medicine formula (after combining the elements of bioactive compound content and the alleged mechanism for curing certain diseases, through a project that is systematically designed) and the alleged mechanism for the cure of certain diseases, through a project that is systematically designed and presented. with quality and measurable performance (C6, A3, P3) | Student inventions (Part-2)
New Formula of Traditional Medicine |
Discovery learning
Cooperative learning Problem Based Learning |
presentation | FF : 2 x (1 x 50 min);
SS: 1 x (2 x 60 min); ST: 1 x (2 x 60 min) |
active in discussion | |
| 15 | Students are able to design a draft patent on the basis of meta-analysis of the proposed formula in competency-7 with quality and measurable performance (C6, A3, P3) | Patents and other intellectual property in traditional medicine
• Types of intellectual property • How to search for patents and drafting |
Discovery learning
Cooperative learning Problem Based Learning |
presentation | FF : 2 x (1 x 50 min);
SS: 1 x (2 x 60 min); ST: 1 x (2 x 60 min) |
active in discussion | |
| 16 | Final exams | Written exam | 90 | The truth and completeness of the answer to the question | |||
| Total Rating | 100 | ||||||
Glossary
GLO = Graduate Learning Outcome
CLO = Course Learning Outcomes
FF = Face to Face Learning
ST = Structured tasks
SS = Self Study
