SEMESTER LEARNING PLAN
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Course Title: Phytochemicals (FK)
MK code: AKM21 345
Credit Weight: 2
Group of Courts: elective
Semester: 6
Prerequisite Course: ES
Lecturer:
Dr. Khairul Anam,M.Si
Dra. Dewi Kusrini,M.Si
Graduate Learning Outcomes (GLO)
| Attitude | GLO1-(S9) | Demonstrate an attitude of responsibility for work in their field of expertise independently. |
| Knowledge | GLO2-(PP1) | Mastering the theoretical concepts of structure, properties, changes, kinetics, and energetics of molecules and chemical systems, identification, separation, characterization, transformation, synthesis of macromolecular chemicals, and their application. |
| General Skills | GLO3-(KU1) | Able to apply logical, critical, systematic, and innovative thinking in the context of the development or implementation of science and technology that pays attention to and uses humanities values by their field of expertise |
| GLO4-(KU2) | Able to demonstrate independent, quality, and measurable performance. | |
| Special skill | GLO5-(KK1) | Able to produce appropriate conclusions based on the identification, analysis, isolation, transformation, and synthesis of chemicals that have been carried out. |
| GLO6-(KK2) | Able to solve science and technology problems in general and straightforward chemical fields such as identification, analysis, isolation, transformation, and synthesis of micro-molecules through the application of knowledge of structure, properties, kinetics, and energetics of molecules and chemical systems, with analytical methods and synthesis in specific chemical fields, as well as the application of relevant technologies. | |
| GLO7-(KK3) | Able to analyze several alternative solutions in identification, analysis, isolation, transformation, and synthesis of available chemicals and present analysis conclusions for appropriate decision making. |
Course Learning Outcomes (CLO)
| CLO-1 | can explain the Role and Dynamics of Pesticides |
| CLO-2 | can explain the classification of pesticides based on how the pesticide enters/works, based on the target organism, based on the level of toxicity |
| CLO-3 | can explain the analysis and handling of the dangers/impacts of using pesticides |
| CLO-4 | can describe the use and formulation of pesticides |
| CLO-5 | capable of exploring and designing materials for pesticides |
| CLO-6 | can determine the qualitative and quantitative tests of pesticides |
Course Description
This course study contains diverse secondary metabolite molecular structures (Terpenoids, steroids, alkaloids, flavonoids, coumarins, phenolic acids, saponins, tannins, lignans, and quinones) and their distribution in plants. Phytochemical Screening, Extraction, Fractionation, Purification, Characterization
| Week | Expected ability (Sub-CLO) | Study Materials/ Learning Materials | Learning methods | Student Learning Experience | Time (minutes) | Evaluation | |
| Criteria and Indicators | % | ||||||
| 1 | Able to understand (C2). Construct (P4) and discuss (A2) the scope and development of natural compound compounds | Preliminary :
– scope – understanding of phytochemicals – the history of the development of phytochemicals – grouping of natural materials |
Discovery learning
Cooperative learning |
listen. Write. Ask. Search.
Collecting and compiling information to describe the scope and history of phytochemical development |
FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
Accuracy explains with
correct at least 80% |
5 |
| 2 | Able to understand (C2). Construct (P4) and discuss (A2) the molecular structure of terpenoids/steroids, alkaloids, flavonoids, and tannins | Secondary Metabolite Molecular Structure:
– terpenoids/steroids – alkaloids – flavonoids – tannins |
Discovery learning
Cooperative learning |
Group discussion comparing the characteristics & diversity of molecular structures and physicochemical properties of terpenoids/steroids, alkaloids, flavonoids, and tannins | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
The accuracy and ability to master the learning outcomes of each learning stage is at least 80% | 10 |
| 3 | Able to understand (C2). Construct (P4) and discuss (A2) the molecular structure of phenolic acids, lignans, coumarins, quinones, and saponins | Secondary Metabolite Molecular Structure:
– phenolic acid – lignans – Coumarin – quinone – saponins |
Discovery learning
Cooperative learning Problem Based Learning |
Group discussion comparing the characteristics & diversity of molecular structures and physicochemical properties of phenolic acids, lignans, coumarins, quinones, and saponins | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
The accuracy and ability to master the learning outcomes of each learning stage is at least 80% | 10 |
| 4 | Able to understand (C2). Construct (P4) and discuss (A2) isolation strategies. Purification, characterization, and identification of the class of triterpenoid/steroid compounds | Triterpenoids/Steroids :
– isolation – purification – identification – characterization – bioactivity |
Discovery learning
Cooperative learning Problem Based Learning |
Lectures and group discussions to develop strategies for isolation, purification, identification, and characterization of triterpenoid/steroid compounds | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
The accuracy and ability to master the learning outcomes of each learning stage is at least 80% | 5 |
| 5 | Able to understand (C2). Construct (P4) and discuss (A2) isolation strategies. Purification, characterization, and identification of groups of alkaloid compounds | alkaloids:
– isolation -purification -identification -characterization – bioactivity |
Discovery learning
Cooperative learning Problem Based Learning |
Lectures and group discussions to develop strategies for isolation, purification, identification, and characterization of triterpenoid/steroid compounds | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
The accuracy and ability to master the learning outcomes of each learning stage is at least 80% | 10 |
| 6 | Able to understand (C2). Construct (P4) and discuss (A2) isolation strategies. Purification, characterization, and identification of phenolic acid compounds | Phenolic Acid:
– isolation -purification -identification -characterization – bioactivity |
Discovery learning
Cooperative learning Problem Based Learning |
Lectures and group discussions to develop strategies for isolation, purification, identification, and characterization of phenolic acid compounds | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
The accuracy and ability to master the learning outcomes of each learning stage is at least 80% | 5 |
| 7 | Able to understand (C2). Construct (P4) and discuss (A2) isolation strategies. Purification, characterization, and identification of tannin compounds | Tannins:
– isolation -purification -identification -characterization – bioactivity |
Problem Based Learning | Lectures and group discussions develop strategies for isolation, purification, identification, and characterization of tannin compounds. | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
The accuracy and ability to master the learning outcomes of each learning stage is at least 80%
|
5 |
| 8 | Midterm exam | Written exam | 90 | Truth in solving exam questions | 50 | ||
| 9 | Able to understand (C2). Construct (P4) and discuss (A2) isolation strategies. Purification, characterization, and identification of flavonoid compounds | Flavonoids:
– isolation -purification -identification -characterization – bioactivity |
Discovery learning
Cooperative learning Problem Based Learning |
Lectures and group discussions develop strategies for isolation, purification, identification, and characterization of flavonoid compounds. | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
The accuracy and ability to master the learning outcomes of each learning stage is at least 80% | 5 |
| 10 | Able to understand (C2). Construct (P4) and discuss (A2) isolation strategies. Purification, characterization, and identification of coumarin. compounds | Coumarin :
– isolation -purification -identification -characterization – bioactivity |
Discovery learning
Cooperative learning Problem Based Learning |
Lectures and group discussions to develop strategies for isolation, purification, identification, and characterization of coumarin compounds | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
The accuracy and ability to master the learning outcomes of each learning stage is at least 80% | 5 |
| 11 | Able to understand (C2). Construct (P4) and discuss (A2) isolation strategies. Purification, characterization, and identification of Lignan compounds | Lignans:
– isolation -purification -identification -characterization – bioactivity |
Discovery learning
Cooperative learning Problem Based Learning |
Lectures and group discussions to develop strategies for isolation, purification, identification, and characterization of lignans compounds | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
The accuracy and ability to master the learning outcomes of each learning stage is at least 80% | 10 |
| 12 | Able to understand (C2). Construct (P4) and discuss (A2) isolation strategies. Purification, characterization, and identification of Saponin compounds
|
Saponins:
– isolation -purification -identification -characterization – bioactivity |
Discovery learning
Cooperative learning Problem Based Learning |
Lectures and group discussions to develop strategies for isolation, purification, identification, and characterization of Saponin compounds | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
The accuracy and ability to master the learning outcomes of each learning stage is at least 80% | 10 |
| 13 | Able to understand (C2). Construct (P4) and discuss (A2) isolation strategies. Purification, characterization, and identification of Quinone compounds | Quinones:
– isolation -purification -identification -characterization – bioactivity |
Discovery learning
Cooperative learning Problem Based Learning |
Lectures and group discussions to develop strategies for isolation, purification, identification, and characterization of quinone compounds | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
The accuracy and ability to master the learning outcomes of each learning stage is at least 80% | 10 |
| 14 | Able to understand (C2). Construct (P4) and discuss (A2) Antidiabetic and antihyperuricemic antimicrobial bioactivity test methods | Bioactivity Testing Method (in vitro- in vivo):
– antimicrobial – antidiabetic – antihyperuricemia |
Discovery learning
Cooperative learning Problem Based Learning |
listen. Write. Ask. Search.
Collect and compile information on antimicrobial bioactivity test methods Antidiabetic and antihyperuricemia |
FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
The accuracy and ability to master the learning outcomes of each learning stage is at least 80% | 5 |
| 15 | Able to understand (C2). Construct (P4) and discuss (A2) Test methods for cytotoxic analgesic and antioxidant bioactivity | Bioactivity Testing Method (in vitro-in vivo):
– analgesic – cytotoxic – antioxidant |
Discovery learning
Cooperative learning Problem Based Learning |
listen. Write. Ask. Search.
Collect and compile information on antimicrobial bioactivity test methods Antidiabetic and antihyperuricemia |
FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
The accuracy and ability to master the learning outcomes of each learning stage is at least 80% | 5 |
| 16 | Final exams | Written exam | 90 | The truth and completeness of the answer to the question | 50 | ||
Reference:
- Cannell, R.J.P et.al, 1998, Natural Products Isolation, Humana Oress, New Jersey
- Mann, J., et.el., 1994, Natural Products, John Wiley & Sons, New York
- Robinson, T., 1991, The Organic Constituents of Higher Plants, 6th. ed., Cordus Press, North Amherst
- Ikan, R., 1991, Natural Products 2nd ed. Academic Press, San Diego
- Geiss F., 1987, Fundamental of TLC, Huthig Verlag, Heidelberg
- Harborne, J.B ., 1987, Metode Fitokimia, Penerbit ITB Bandung
- Murray, R.D.H., Mendez, J., Brown, S.A., 1982, The natural Coumarins, John Wiley & Sons, New York
- Cordell, G.A., 1981, Introductions to Alkaloids, John Wiley & Sons, New York
- Mabry, T.J., 1970, The systematics Identification of Flavonoids, Springer-Verlag, New York
- Farnsworth, N.R., 1966, Biological and Phytochemical Screening of Plants, J.Pharm. Sci. 66 (3)
Glossary
GLO = Graduate Learning Outcome
CLO = Course Learning Outcomes
FF = Face to Face Learning
ST = Structured tasks
SS = Self Study
