SEMESTER LEARNING PLAN
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Course Title: Biochemistry 1 (Bio1)
MK code: AKM21 345
Credit Weight: 3
Group of Courts: Compulsory
Semester: 4
Prerequisite Course: KD2
Lecturer:
Purbowatiningrum RS., M.Si.
Graduate Learning Outcomes (GLO)
| Attitude | GLO1-(S9) | Demonstrate an attitude of responsibility for work in their field of expertise independently. |
| Knowledge | GLO2-(PP1) | Mastering the theoretical concepts of structure, properties, changes, kinetics, and energetics of molecules and chemical systems, identification, separation, characterization, transformation, synthesis of macromolecular chemicals, and their application. |
| General Skills | GLO3-(KU1) | Able to apply logical, critical, systematic, and innovative thinking in the context of the development or implementation of science and technology that pays attention to and uses humanities values by their field of expertise |
| GLO4-(KU2) | Able to demonstrate independent, quality, and measurable performance. |
Course Learning Outcomes (CLO)
| CLO-1 | “Able to explain, understand, and implement chemical concepts in the Cell Molecular Organization and Cell Structure Organization hierarchy.” |
| CLO-2 | Able to explain and understand the characteristics of the biomolecules that make up cells |
| CLO-3 | Able to explain, understand the characteristics of complex biomolecules that make up cell membranes and implement (P2) chemical concepts in the structure and function of biomolecules in cell membrane transport systems |
| CLO-4 | Able to explain, understand the characteristics of the amino acids that make up Protein and the three-dimensional structure of proteins, implement them in the application of chemical concepts in studying the three-dimensional structure of proteins |
| CLO-5 | Able to explain Protein as Biocatalyst (Enzyme): structure, mechanism, kinetics, and inhibition of enzymatic reactions. |
| CLO-6 | Able to explain and understand the structure and function of nucleic acids |
| CLO-7 | Able to explain and understand the mechanism of the concept of protein synthesis |
Course Description
This course studies biochemical aspects: cell constituent components, composition, structure, and function of biomolecules in cells, proteins as biocatalysts: structure, mechanism, kinetics, and inhibition of enzymatic reactions, structure and function of nucleic acids (DNA & RNA) in a cell.
| Week | Expected ability (Sub-CLO) | Study Materials/ Learning Materials | Learning methods | Student Learning Experience | Time (minutes) | Evaluation | |
| Criteria and Indicators | % | ||||||
| 1 | Students can explain, understand (C2) and implement (P2) chemical concepts in
Hierarchy of Cell Molecular Organization and Cell Structure Organization |
Overview of the Biological Chemistry course on the composition, structure, and function of the biomolecules that make up cells. | Discovery learning
Cooperative learning |
Learn by digging/searching for information and utilizing that information to solve factual problems/ designed by the lecturer | FF: 1 x (3 x 50”)
ST + SS: 1 x [(3 x 50”) + (3 x 60”)] |
Explain and understand
1. The parts of a living cell. 2. Function of each organelle 3. Organization of molecules in cells 4. Use of energy in living systems to maintain their structure |
5 |
| 2 | Students can explain (C2) the characteristics of carbohydrate biomolecules that make up cell membranes and implement (P2) chemical concepts in the structure and function of carbohydrates in cell membranes. | Structure, nature, and function of carbohydrates (amylose, amylopectin, cellulose, glycogen, etc.) as components of cell membranes and non-membranes. | Discovery learning
Cooperative learning |
Learn by digging/searching for information and utilizing that information to solve factual problems/ designed by the lecturer | FF: 1 x (3 x 50”)
ST + SS: 1 x [(3 x 50”) + (3 x 60”)] |
(1). Accuracy and understanding of the structure and function of carbohydrates in cell membranes
(2). Student activity in discussions and doing assignments. |
10 |
| 3 | Students can explain (C2) the characteristics of carbohydrate biomolecules that make up cell membranes and implement (P2) chemical concepts in the structure and function of carbohydrates in cell membranes. | Structure properties of complex carbohydrates (glycolipids, glycoproteins, proteoglycans, etc.) | Discovery learning
Cooperative learning Problem Based Learning |
Learn by digging/searching for information and utilizing that information to solve factual problems/ designed by the lecturer | FF: 1 x (3 x 50”)
ST + SS: 1 x [(3 x 50”) + (3 x 60”)] |
(1). Accuracy and understanding of the structure, properties, and functions of complex carbohydrates in cell membranes
(2). Student activity in discussions and doing assignments. |
5 |
| 4 | Students can explain, understand (C2) the characteristics of lipid biomolecules that make up cell membranes and implement (P2) chemical concepts in the structure and function of carbohydrates in cell membranes and membrane transport | Structure, properties, and function of simple lipids as components of cells | Discovery learning
Cooperative learning Problem Based Learning |
Learn by digging/searching for information and utilizing that information to solve factual problems/ designed by the lecturer | FF: 3 x 50
ST: 3 x 60 SS: 3 x 60 |
(1). Accuracy and understanding of the structure, properties, and function of lipids in cell membranes
(2). Student activity in discussions and doing assignments. |
5 |
| 5 | Students can explain, understand (C2) the characteristics of complex lipid biomolecules that make up cell membranes and implement (P2) chemical concepts in the structure and function of complex lipids in cell membranes and membrane transport using schematics and drawings of at least 70% | Structure, properties, and function of complex lipids as constituent components of cells: triglycerides, phospholipids, cholesterol, steroids, waxes, sphingolipids, prenolipids, sacarolipids, polyketides, lipoproteins, etc. | Discovery learning
Cooperative learning Problem Based Learning |
Learn by digging/searching for information and utilizing that information to solve factual problems/ designed by the lecturer | FF: 3 x 50
ST: 3 x 60 SS: 3 x 60 |
(1). Accuracy and understanding of the structure, properties, and function of complex lipids in cell membranes
(2). Student activity in discussions and doing assignments. |
10 |
| 6 | Students can explain (C2) the characteristics of complex protein biomolecules that make up cell membranes and implement (P2) chemical concepts in the structure and function of carbohydrates in cell membranes and membrane transport. | The structure, properties, and functions of complex proteins as constituent components of cells: triglycerides, phospholipids, cholesterol, steroids, waxes, sphingolipids, prenolipids, sacarolipids, polyketides, lipoproteins, etc. | Discovery learning
Cooperative learning Problem Based Learning |
Learn by digging/searching for information and utilizing that information to solve factual problems/ designed by the lecturer | FF: 3 x 50
ST: 3 x 60 SS: 3 x 60 |
(1). Accuracy and understanding of the structure, properties, and function of complex proteins in cell membranes
(2). Student activity in discussions and doing assignments. |
5 |
| 7 | Students can explain (C2) the characteristics of complex biomolecules that make up cell membranes and implement (P2) chemical concepts in the structure and function of biomolecules in cell membrane transport systems. | The role of biomolecules that make up cell membranes in the transport system between cell membranes | Problem Based Learning | Learn by digging/searching for information and utilizing that information to solve factual problems/ designed by the lecturer | FF: 3 x 50
ST: 3 x 60 SS: 3 x 60 |
(1). Accuracy and understanding of the structure, nature, and function of biomolecules that make up cell membranes in transport between cell membranes
(2). Student activity in group discussions and doing assignments. |
10 |
| 8 | Midterm exam | Written exam | 90 | Truth in solving exam questions | |||
| 9 | Students can explain, understand (C2) the characteristics of the amino acids that make up Proteins and the three-dimensional structure of proteins and implement them (P2) in applying chemical concepts in studying protein structure. | Types and Properties of Amino Acids
Protein types and functions: fibrous and globular proteins. |
Discovery learning
Cooperative learning Problem Based Learning |
Learn by digging/searching for information and utilizing that information to solve factual problems/ designed by the lecturer | FF: 3 x 50
ST: 3 x 60 SS: 3 x 60 |
(1). Accuracy and understanding of the structure, properties, and functions of amino acids
(2). Student activity in group discussions and doing assignments. |
10 |
| 10 | Students can explain, understand (C2) the characteristics of the amino acids that make up Proteins and the three-dimensional structure of proteins and implement them (P2) in applying chemical concepts in studying proteins. | Protein structure: primary, secondary, tertiary, and quaternary structures
Factors affecting the stability of protein structure. |
Discovery learning
Cooperative learning Problem Based Learning |
Learn by digging/searching for information and utilizing that information to solve factual problems/ designed by the lecturer | FF: 3 x 50
ST: 3 x 60 SS: 3 x 60 |
(1). Accuracy and understanding of proteins’ structure, properties, and function with the three-dimensional structure of proteins.
(2) Accuracy in understanding the factors that affect the stability of protein structure (3). Student activity in group discussions and doing assignments. |
10 |
| 11 | Students can explain, understand (C2) the characteristics of the amino acids that make up Proteins and the three-dimensional structure of proteins and implement them (P2) in applying chemical concepts in studying proteins as biocatalysts. | Enzyme components: holoenzyme, apoenzyme, cofactor and coenzyme
Enzyme Classification |
Discovery learning
Cooperative learning Problem Based Learning |
Learn by digging/searching for information and utilizing that information to solve factual problems/ designed by the lecturer | FF: 3 x 50
ST: 3 x 60 SS: 3 x 60 |
(1). Accuracy and understanding of the structure, properties of proteins as biocatalysts
(2). Student activity in group discussions and doing assignments. |
10 |
| 12-13 | Students can explain, understand (C2) the characteristics of the amino acids that make up Proteins and the three-dimensional structure of proteins and implement them (P2) in applying chemical concepts in studying proteins as biocatalysts. | Enzymatic reaction mechanism
Kinetics and inhibition of enzymatic reactions |
Discovery learning
Cooperative learning Problem Based Learning |
Learn by digging/searching for information and utilizing that information to solve factual problems/ designed by the lecturer | FF: 3 x 50
ST: 3 x 60 SS: 3 x 60 |
(1). Accuracy and understanding of enzyme mechanisms and kinetics, enzyme inhibition
(2). Student activity in group discussions and doing assignments. |
10 |
| 14 | Students can understand and explain (C2) and apply (P2) in the Structure and Function of Nucleic Acids in Cells | The structure and function of nucleic acids in cells. – DNA structure and function
– RNA structure and function |
Discovery learning
Cooperative learning Problem Based Learning |
Learn by digging/searching for information and utilizing that information to solve factual problems/ designed by the lecturer | FF: 3 x 50
ST: 3 x 60 SS: 3 x 60 |
(1). Accuracy and understanding of the structure, nature, and function of DNA and RNA and nucleic acids
(2). Student activity in group discussions and doing assignments. |
10 |
| 15 | Students can understand and explain (C2) and apply (P2) in the Structure and Function of Nucleic Acids in protein synthesis | Protein Biosynthesis | Discovery learning
Cooperative learning Problem Based Learning |
Learn by digging/searching for information and utilizing that information to solve factual problems/ designed by the lecturer | FF: 3 x 50
ST: 3 x 60 SS: 3 x 60 |
(1). Accuracy and understanding of the role of DNA and RNA in protein synthesis
(2). Student activity in group discussions and doing assignments. |
10 |
| 16 | Final exams | Written exam | 90 | The truth and completeness of the answer to the question | |||
| Total Rating | 100 | ||||||
Reference:
- Devlin, T.M., (2010), Textbook of Biochemistry With Clinical Correlations, Nine Edition, Wiley-Liss, Inc, USA.
- Lehninger, (2013), Biochemistry, five edition, Worth Publisher, Inc, USA.
- Mathews, C.K., and Van Holde, K.E., (2013), Biochemistry, 4th edition, The Benjamin/Cummings Publishing Company, Inc, California, USA.
- Voet, D., and Voet, J.G., (2011), Biochemistry, John Wiley and Sons, New York, USA.
Glossary
GLO = Graduate Learning Outcome
CLO = Course Learning Outcomes
FF = Face to Face Learning
ST = Structured tasks
SS = Self Study
