SEMESTER LEARNING PLAN
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Course Title: Elucidation of Molecular Structure of Organic Compounds (ES)
MK code: AKM21 364
Credit Weight: 2
Group of Courts: Compulsory
Semester: 6
Prerequisite Course: KO3, AO
Lecturer:
Dra. Dewi Kusrini, M.Si
Dr. Khairul Anam, M.Si
Graduate Learning Outcomes (GLO)
| Attitude | GLO1-(S9) | Demonstrate an attitude of responsibility for work in their field of expertise independently. |
| Knowledge | GLO2-(PP1) | Mastering the theoretical concepts of structure, properties, changes, kinetics, and energetics of molecules and chemical systems, identification, separation, characterization, transformation, synthesis of macromolecular chemicals, and their application. |
| GLO3-(PP2) | Mastering complete operational knowledge of functions, operating standard chemical instruments, and analyzing data and information from these instruments. | |
| GLO4-(PP3) | Mastering the basic principles of software for analysis, synthesis, and molecular modeling in general or more specific chemical fields. | |
| General Skills | GLO5-(KU1) | Able to apply logical, critical, systematic, and innovative thinking in the context of the development or implementation of science and technology that pays attention to and uses humanities values by their field of expertise |
| GLO6-(KU2) | Able to demonstrate independent, quality, and measurable performance. | |
| GLO7-(KU5) | Able to make decisions regularly in the context of solving problems in their area of expertise, based on the results of analysis of information and data. | |
| Special skill | GLO8-(KK2) | Able to solve science and technology problems in general chemistry and simple scopes such as identification, analysis, isolation,transformation, and synthesis of micro-molecules through the application of knowledge of the structure, properties, kinetics, and energetics of molecules and chemical systems, with analysis and synthesis methods in specific chemical fields, as well as the application of relevant technologies |
| GLO9-(KK3) | Able to analyze several alternative solutions in identification, analysis, isolation, transformation, and synthesis in the available chemical fields and present analysis conclusions to make the right decisions. | |
| GLO10-(KK4) | Able to use software to determine the structure and energy of micromolecules, software to assist analysis and synthesis in general or more specific chemical fields (organic, biochemical, or inorganic), and data processing. |
Course Learning Outcomes (CLO)
| CLO-1 | Able to explain, understand and analyze UV-Vis spectroscopy |
| CLO-2 | able to define, understand and analyze Infrared (IR) Spectroscopy |
| CLO-3 | able to determine, understand and analyze Gc. Spectroscopy-Mass |
| CLO-4 | able to explain, understand and analyze LC. Spectroscopy-Mass |
| CLO-5 | able to define, understand and analyze 1HNMR |
| CLO-6 | able to define, understand and analyze 13CNMR |
| CLO-7 | able to determine the molecular structure of an organic compound based on the spectrum of UV-vis, IR, mass, and NMR. |
Course Description
This course studies the elucidation of the molecular structure of organic compounds based on the spectrum from UV-Vis spectroscopy, Infrared Spectroscopy, Mass Spectroscopy, and NMR spectroscopy.
| Week | Expected ability (Sub-CLO) | Study Materials/ Learning Materials | Learning methods | Student Learning Experience | Time (minutes) | Evaluation | |
| Criteria and Indicators | % | ||||||
| 1-2 | able to explain, understand and analyze UV-Vis spectroscopy | Atomic structure, molecular structure, qualitative analysis, quantitative analysis, separation concepts, mathematics | Discovery learning
Cooperative learning |
Group discussion, determine the absorption (λmax ) of an organic compound and interpretation of the UV-Vis spectrum of an organic compound | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accurately explain and analyze electromagnetic energy.
• Accuracy in explaining and analyzing absorption law both qualitatively and quantitatively. • Accurately explain and analyze the effect of solvents. • Accuracy describes how to calculate (λmax). • Accuracy of explaining and interpreting the UV-Vis spectrum |
10 |
| 3-4 | Able to explain, understand and analyze Infrared (IR) spectroscopy | Atomic structure, molecular structure, qualitative analysis, quantitative analysis, separation concepts, physics, mathematics | Discovery learning
Cooperative learning Problem Based Learning |
Group discussion, calculating the vibrational frequency of functional groups, and Interpreting the IR spectrum of an organic compound | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accuracy describes the molecular vibration of an organic compound
• Accuracy in explaining the factors that affect the vibration frequency. • Accuracy of explaining and analyzing the Infrared spectrum |
10 |
| 5-6 | Able to explain, understand and analyze Mass spectroscopy (GC-MS) | Atomic structure, Molecular structure, compound reactivity, qualitative analysis, quantitative analysis, separation concept | Discovery learning
Cooperative learning Problem Based Learning |
Group discussion, determine the fragmentation pattern of the mass spectrum of organic compounds (aromatic, aliphatic) from the results of GC-MS analysis. | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accuracy in explaining the basics of mass spectroscopy.
• Accuracy describes the molecular ion. • Accuracy describes the even-electron rule or the nitrogen rule. • Accuracy describes the fractionation associated with the functional group. • Precise fragmentation of the GC-MS spectrum |
15 |
| 7 | Able to explain, understand and analyze Mass Spectroscopy (LC-MS) | Atomic structure, Molecular structure, compound reactivity, qualitative analysis, quantitative analysis, separation concept | Discovery learning
Cooperative learning Problem Based Learning |
Group discussion, determine the fragmentation pattern of the mass spectrum of organic compounds (aromatic, aliphatic) from the results of LC-MS analysis. | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accuracy in explaining the basics of LC-MS.
• Accuracy in explaining the effect of the solvent. • The accuracy of determining the types of ionizers. • Accurate interpretation of the LC-MS spectrum |
10 |
| 8 | Midterm exam | Written exam | 90 | Truth in solving exam questions | |||
| 9-11 | Able to explain, understand and analyze Core Magnetic Resonance Spectroscopy (1HNMR) | Atomic structure, Molecular structure, compound reactivity, qualitative analysis, quantitative analysis, separation concept | Discovery learning
Cooperative learning Problem Based Learning |
Group Discussion: determine the chemical shift region of protons (H atoms) contained in an organic compound | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accuracy describes the effect of the magnetic field on the nucleus.
• Accuracy in explaining the absorption mechanism (resonance). • Accuracy in explaining proton chemical shift • Accuracy in explaining intra-molecular factors • Accuracy of explaining spin-spin solving law • Accuracy of explaining about cash coupling • Accuracy of interpreting the 1HNMR spectrum |
15 |
| 12-13 | Able to explain, understand and analyze Core Magnetic Resonance Spectroscopy (13CNMR) | Atomic structure, Molecular structure, compound reactivity, qualitative analysis, quantitative analysis, separation concept | Discovery learning
Cooperative learning Problem Based Learning |
Group Discussion: determine the chemical shift region of carbon-13 (C atom) contained in an organic compound | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• The accuracy of calculating the chemical shift formula
• Accuracy describes a constant coupling • Accuracy of explaining de-coupling • The accuracy of interpreting the 13CNMR spectrum |
15 |
| 14 | Able to determine the molecular structure of organic compounds. Based on UV-Vis, IR, Mass and NMR spectra (1HNMR and 13CNMR) | Atomic structure, molecular structure, the reactivity of compounds, qualitative analysis, quantitative analysis, separation concept | Discovery learning
Cooperative learning Problem Based Learning |
Group discussion: Determine the molecular structure of organic compounds. | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accurate interpretation of the UV-Vis spectrum
• The accuracy of interpreting the infrared (IR) spectrum • The accuracy of interpreting the mass spectrum (GC-MS). • Accuracy in interpreting the NMR spectrum (1HNMR and 13CNMR) |
10 |
| 15 | Able to determine the molecular structure of organic compounds. Based on UV-Vis, IR, Mass and NMR spectra (1HNMR and 13CNMR) | Atomic structure, Molecular structure, compound reactivity, qualitative analysis, quantitative analysis, separation concept | Discovery learning
Cooperative learning Problem Based Learning |
Group discussion: Determine the molecular structure of organic compounds. | FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• The accuracy of interpreting the UV-Vis spectrum.
• The accuracy of interpreting the infrared (IR) spectrum • The accuracy of interpreting the mass spectrum (GC-MS). • Accuracy in interpreting the NMR spectrum (1HNMR and 13CNMR) |
10 |
| 16 | Final exams | Written exam | 90 | The truth and completeness of the answer to the question | |||
| Total Rating | 100 | ||||||
Reference:
- Silverstein, R.M dan Bassler, G.C., 1967, Spektrometric Identification of Organic Compounds, 2nd edition, John Wiley and and Sons, New York.
- William Kemp, 1975, Organic Spectroscopy, ELBS and the Mac Millan Press Ltd.
- Kalinowski, H,O., S. Berger, S. Braun. 1988, Carbon-13 NMR Spectroscopy. Printed and bound in Great Britain by St.Edmundsbury Press. John Willey and Sons. New York.
- Furnis B.S., Hannaford A.J., Smith P.W.G., Tatchell A.R., 1989, Vogel’s Textbook of Practical Organic Chemistry, edisi 5, Longman Scientific and Technical, New York.
- Shriner R.L., Fuson R.C., Curtin D.Y., Morril t.c., 1980, The Sistematic Identification of Organic Chemistry, edisi6, John Wiley and Sons, New York.
Glossary
GLO = Graduate Learning Outcome
CLO = Course Learning Outcomes
FF = Face to Face Learning
ST = Structured tasks
SS = Self Study
