SEMESTER LEARNING PLAN
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Course Title: Natural Materials Chemistry (BA)
MK code: AKM21 454
Credit Weight: 2
Group of Courts: elective
Semester: 5
Prerequisite Course: KO3
Lecturer:
Dr. Meiny Suzery, MS,
Dra. Dewi Kusrini, M.Si
Graduate Learning Outcomes (GLO)
| Attitude | GLO1-(S9) | Demonstrate an attitude of responsibility for work in their field of expertise independently. |
| Knowledge | GLO2-(PP1) | Mastering the theoretical concepts of structure, properties, changes, kinetics, and energetics of molecules and chemical systems, identification, separation, characterization, transformation, synthesis of micromolecular chemicals, and their application. |
| General Skills | GLO 3 -(KU1) | Able to apply logical, critical, systematic, and innovative thinking in the context of the development or implementation of science and technology that pays attention to and uses humanities values by their field of expertise |
| GLO 4 -(KU2) | Able to demonstrate independent, quality, and measurable performance |
Course Learning Outcomes (CLO)
| CLO-1 | can explain the classification & biogenetic origin of secondary metabolite compounds. |
| CLO-2 | can explain the classification of secondary metabolites based on regularity. |
| CLO-3 | can explain several chemical reactions & synthesis of terpenoids, phenylpropanoids, polyketides, flavonoids, and alkaloids |
| CLO-4 | can describe the classification & structural variations of various terpenoids, phenylpropanoids, polyketides, flavonoids, and alkaloids |
| CLO-5 | can explore and design metabolites in living organisms |
| CLO-6 | can explain several organic reactions related to the determination of the structure of terpenoids, phenylpropanoids & polyketides, flavonoids, and alkaloids |
| CLO-7 | can show the role & benefits of several organic compounds from natural ingredients |
Course Description
This course studies the origin of natural biological compounds (plants, animals, and microorganisms). It can compare the classification, biosynthetic processes, synthesis, and properties of secondary metabolites (essential oils, triterpenoids, steroids, phenylpropanoids-polyketides, alkaloids, and flavonoids).
| Week | Expected ability (Sub-CLO) | Study Materials/ Learning Materials | Learning methods | Student Learning Experience | Time (minutes) | Evaluation | |
| Criteria and Indicators | % | ||||||
| 1 | able to explain (C2) the origin of natural biological compounds and how biomolecules can be a solution to overcome health and environmental problems | Definition, the source of natural biological compounds | Discovery learning
Cooperative learning |
Group discussion, formulating the proper meaning of the notion of biomolecules | FF: 1 x (2 x 50”)
ST + SS: 1 x [(2 x 50”) + (2 x 60”)] |
• Accuracy in explaining the relationship of organic molecules in the tissues of living organisms
• Accuracy in explaining the metabolism of biomolecule formation |
5 |
| 2 | able to define primary & secondary metabolism | Inter-molecular and biomolecular interactions | Discovery learning
Cooperative learning |
Task 1: students are asked to look for one of the primary and secondary metabolites in natural ingredients complete with molecular structure | FF: 1 x (2 x 50”)
ST + SS: 1 x [(2 x 50”) + (2 x 60”)] |
• Accuracy of explaining primary metabolism with secondary metabolism
• Accuracy in explaining primary and secondary metabolite products and their functions and uses |
5 |
| 3 | able to explain the terpenoid group
|
Molecular Structure, Intermolecular Interaction, Biomolecules | Discovery learning
Cooperative learning Problem Based Learning |
group discussion concludes the formation of terpenoids through biosynthetic order | FF: 1 x (2 x 50”)
ST + SS: 1 x [(2 x 50”) + (2 x 60”)] |
• Accuracy in explaining the biosynthesis of terpenoids (mono, seskui, tri, and polyterpenes) | 5 |
| 4-5 | able to explain the process of biosynthesis of terpenoid compounds (essential oils) | Molecular structure, the reactivity of compounds, reactions of compounds, interactions between molecules | Discovery learning
Cooperative learning Problem Based Learning |
FF: 1 x (2 x 50”)
ST + SS: 1 x [(2 x 50”) + (2 x 60”)] |
• The accuracy of concluding the process of forming essential oils | 10 | |
| 6-7 | able to explain summarizing triterpene and steroid compounds | Molecular structure, the reactivity of compounds, reactions of compounds, interactions between molecules
• Steroid biosynthesis • Biological activity |
Discovery learning
Cooperative learning Problem Based Learning |
group discussion concludes the formation of triterpenoids/steroids through biosynthetic order
Task 2: students are asked to look for one of the essential oil compounds in natural ingredients, complete with isolation techniques, determination of molecular structures, activity tests |
FF: 1 x (2 x 50”)
ST + SS: 1 x [(2 x 50”) + (2 x 60”)] |
• Accuracy in explaining triterpene/steroid biosynthesis
• Accuracy in designing triterpene/steroid compounds • Accuracy in explaining the relationship between the structure and reactivity of compounds in physiological functions in the body |
10 |
|
8
|
|
Midterm exam | Written exam | 90 | The truth and completeness of the answer to the question | ||
| 9-10 | Describe some organic reactions related to the determination of the structure of polyketides | Molecular structure, the reactivity of compounds, reactions of compounds,
intermolecular interactions • Steroid biosynthesis • Biological activity |
Discovery learning
Cooperative learning Problem Based Learning |
group discussion concluded the formation of phenylpropanoid and polyketide through biosynthetic order | FF: 1 x (2 x 50”)
ST + SS: 1 x [(2 x 50”) + (2 x 60”)] |
• Accuracy in describing the goal compound. Polyketides and their properties with people’s reactions related to structural determination | 10 |
| 11 | Describe the classification & biogenetic origin of alkaloids | Molecular structure, compound reactions, intermolecular interactions
• Steroid biosynthesis • Biological activity of steroids |
Discovery learning
Cooperative learning Problem Based Learning |
FF: 1 x (2 x 50”)
ST + SS: 1 x [(2 x 50”) + (2 x 60”)] |
• The accuracy of designing the process of alkaloid compounds | 5 | |
| 12 | able to explain some chemical reactions & the synthesis of alkaloids | Compound Reaction, Intermolecular Interaction / Biomaterial Engineering | Discovery learning
Cooperative learning Problem Based Learning |
Task 3: students are asked to look for one of the alkaloid compounds in natural materials, complete with isolation techniques, determination of molecular structures, activity tests | FF: 1 x (2 x 50”)
ST + SS: 1 x [(2 x 50”) + (2 x 60”)] |
Accuracy of reaction design: Hofmann & Emde degradation Von Braun reaction and rearrangement Synthesis of several alkaloids | 10 |
| 13 | able to explain the classification & structural variation of various flavonoids | Compound Reaction, Intermolecular Interaction/ Biomaterial Engineering | Discovery learning
Cooperative learning Problem Based Learning |
FF: 1 x (2 x 50”)
ST + SS: 1 x [(2 x 50”) + (2 x 60”)] |
• Accuracy in describing the flavonoid group of compounds and their properties in relation to people’s reactions to the determination.
|
5 | |
| 14 | able to explain specific reactions & flavonoid synthesis | Molecular structure, compound reactions, intermolecular interactions
• Biosynthesis of flavonoids • Biological activity of flavonoids • Relationships between structures |
Discovery learning
Cooperative learning Problem Based Learning |
FF: 1 x (2 x 50”)
ST + SS: 1 x [(2 x 50”) + (2 x 60”)] |
• Accuracy in designing the process of flavonoid compounds | 10 | |
| 15 | able to design the synthesis of flavonoids to increase the bioactivity of biomolecules and the role & benefits of several organic compounds from natural ingredients | Molecular structure, compound reactions, intermolecular interactions
• Biosynthesis of flavonoids • Biological activity of flavonoids |
Discovery learning
Cooperative learning Problem Based Learning |
Task 4: students are asked to look for one of the flavonoid compounds in natural ingredients, complete with isolation techniques, determination of molecular structures, activity tests | FF: 1 x (2 x 50”)
ST + SS: 1 x [(2 x 50”) + (2 x 60”)] |
• Precisely designing biomolecules to enhance the activity | 10 |
| 16 | Final exams | Written exam | 90 | The truth and completeness of the answer to the question | |||
| Total Rating | 100 | ||||||
Reference:
- Manitto, P., 1992, Biosintesis Produk Alami (terjemahan oleh Dra. Koensoemardiyah, Apt. SU.), IKIP Semarang Press.
- Achmad, S.A., 1985, Kimia Organik Bahan Alam, Modul 1 – 3, Dep. P & K Universitas Terbuka
- Achmad, S.A., 1985, Kimia Organik Bahan Alam, Modul 4 – 6, Dep. P & K Universitas Terbuka
Glossary
GLO = Graduate Learning Outcome
CLO = Course Learning Outcomes
FF = Face to Face Learning
ST = Structured tasks
SS = Self Study
