SEMESTER LEARNING PLAN
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Course Title: Biomaterial Design (BM)
MK code: AKM21 546
Credit Weight: 2
Group of Courts: Elective
Semester: 4
Prerequisite Course: ENG
Lecturer:
Tri Windarti, M.Si
Graduate Learning Outcomes (GLO)
| Attitude | GLO1-(S9) | Demonstrate an attitude of responsibility for work in their field of expertise independently. |
| Knowledge | GLO2-(PP1) | Mastering the theoretical concepts of structure, properties, changes, kinetics, and energetics of molecules and chemical systems, identification, separation, characterization, transformation, synthesis of macromolecular chemicals, and their application. |
| General Skills | GLO3-(KU1) | Able to apply logical, critical, systematic, and innovative thinking in the context of the development or implementation of science and technology that pays attention to and uses humanities values by their field of expertise |
| GLO4-(KU2) | Able to demonstrate independent, quality, and measurable performance. |
Course Learning Outcomes (CLO)
| CLO-1 | can explain (C2) the part of the human body that is most often damaged and how biomaterials can be a solution to overcome them and can explain how biomaterials can be a solution to overcome them. |
| CLO-2 | can explain the bulky and surface properties of a material |
| CLO-3 | can explain the physiological conditions of the human body and the functions of several organs |
| CLO-4 | can describe the properties of metals, polymers, ceramics, and composites as biomaterials along with their advantages and disadvantages, as well as examples of applications |
| CLO-5 | capable of designing chemical engineering and biomaterial surfaces |
| CLO-6 | can determine the proper test for the characterization of biomaterials from material determination to biomaterials that can be applied to humans |
| CLO-7 | can design biomaterials for artificial bones to overcome bone damage due to osteoporosis by using calcium phosphate as a base material and perform chemical and surface engineering to increase the biomaterial’s bioactivity. |
Course Description
This course studies biomaterials, a material placed in the human body to replace the function of a part, either temporarily or permanently. To be able to carry out its function, the material must meet several Physico-chemical and surface requirements. Designs that include chemical and surface engineering will be studied, along with the analytical techniques used.
| Week | Expected ability (Sub-CLO) | Study Materials/ Learning Materials | Learning methods | Student Learning Experience | Time (minutes) | Evaluation | |
| Criteria and Indicators | % | ||||||
| 1 | Able to explain (C2) the parts of the human body that are most frequently damaged and how biomaterials can be a solution to overcome them | The concept of solids. Biomaterial needs at this time | Discovery learning
Cooperative learning |
Group discussion, formulating the correct definition of the notion of biomaterials
Task: Sample implant |
FF: 1 x (2 x 50”)
ST + SS: 1 x [(2 x 50”) + (2 x 60”)] |
• Accuracy describes the parts of the human body that are most often damaged
• Accuracy explains how biomaterials can be a solution for organ damage |
5 |
| 2 | Able to explain how biomaterials can be a solution to overcome them | 1. Properties of biomaterials
2. Regulation of the use of biomaterials |
Discovery learning
Cooperative learning |
Group discussion, arranging body parts that biomaterials can replace
Task: Examples of regulation of the use of biomaterials |
FF: 1 x (2 x 50”)
ST + SS: 1 x [(2 x 50”) + (2 x 60”)] |
• Accuracy describes the properties of biomaterials
• Accuracy of explaining the steps so that the biomaterial can be allowed to be applied to humans |
10 |
| 3 | Able to explain the bulky nature of a material | Material Properties: Bulky Material Properties | Discovery learning
Cooperative learning Problem Based Learning |
Group discussion, factors that affect the bulky nature of a material
Task: Examples of bulky properties of some materials |
FF: 1 x (2 x 50”)
ST + SS: 1 x [(2 x 50”) + (2 x 60”)] |
• Accuracy describes the bulky nature of a material | 5 |
| 4 | Able to explain the surface properties of a material | Material Properties: Material Surface Properties | Discovery learning
Cooperative learning Problem Based Learning |
Group discussion, factors that affect the surface properties of a material
Task: Examples of surface properties of some materials |
FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accuracy describes the surface properties of a material | 5 |
| 5 | Able to explain the physiological conditions of the human body and the functions of several organs | Physiological Conditions:
1. Human body system 2. Functions of body organs |
Discovery learning
Cooperative learning Problem Based Learning |
Group discussion, systems in the body
Task: The complexity of the function of an organ |
FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accuracy describes human body systems such as human body fluids
• Accuracy in explaining the function of body organs such as human bones |
5 |
| 6 | Be able to describe the properties of metals as biomaterials along with their advantages and disadvantages as well as examples of applications | Materials for Biomaterial: Metal
|
Discovery learning
Cooperative learning Problem Based Learning |
Group discussion, metal properties
Task: use of metals as biomaterials |
FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accuracy in describing the properties of metals as biomaterials along with their advantages and disadvantages | 5 |
| 7 | Able to describe the properties of polymers as biomaterials along with their advantages and disadvantages as well as application examples | Material for Biomaterial: Polymer | Problem Based Learning | Group discussion, polymer properties
Task: use of polymers as biomaterials |
FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
•Accuracy in describing the properties of polymers as biomaterials along with their advantages and disadvantages | 5 |
| 8 | Midterm exam | Written exam | 90 | Truth in solving exam questions | |||
| 9 | Able to describe the properties of ceramics as biomaterials along with their advantages and disadvantages as well as application examples | Material for Biomaterial: Ceramic | Discovery learning
Cooperative learning Problem Based Learning |
Group discussion, properties of ceramics
Task: use of ceramics as a biomaterial |
FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accuracy in describing the properties of ceramics as biomaterials and their advantages and disadvantages | 5 |
| 10 | Able to describe composite properties as biomaterials along with their advantages and disadvantages as well as application examples | Material for Biomaterials: Composite | Discovery learning
Cooperative learning Problem Based Learning |
Group discussion, properties of ceramics
Task: use of ceramics as a biomaterial |
FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accuracy in describing the properties of composites as biomaterials and their advantages and disadvantages | 5 |
| 11 | Able to design chemical engineering and biomaterial surfaces | Biomaterials Engineering: Chemical Engineering | Discovery learning
Cooperative learning Problem Based Learning |
Group discussion, methods used in chemical engineering
Assignment: examples of chemical engineering on biomaterials |
FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accuracy in designing chemical engineering and biomaterial surfaces | 10 |
| 12 | Able to design chemical engineering and biomaterial surfaces | Biomaterials Engineering: Surface Engineering | Discovery learning
Cooperative learning Problem Based Learning |
Group discussion, the method used in surface engineering
Assignment: examples of surface engineering on biomaterials |
FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accuracy in designing chemical engineering and biomaterial surfaces | 10 |
| 13 | Able to determine the proper test for the characterization of biomaterials from material determination to biomaterials that can be applied to humans | Biomaterial Characterization:
1. Chemical Characterization 2. Physical Characterization 3. Surface Characterization |
Discovery learning
Cooperative learning Problem Based Learning |
Group discussion, characterization method
Assignment: example 1. Chemical Characterization 2. Physical Characterization 3. Surface Characterization |
FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accuracy determines the appropriate test for biomaterial characterization | |
| 14 | Able to determine the proper test for the characterization of biomaterials from material determination to biomaterials that can be applied to humans | Biomaterial Characterization: 1. In Vitro Test 2. In vivo Test | Discovery learning
Cooperative learning Problem Based Learning |
Group discussion, differences in vitro and in vivo tests
Task: example 1. in vitro test 2. in vivo test |
FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
•Accuracy describes in vitro tests and in vivo tests on surface biomaterials | 10 |
| 15 | Able to design biomaterials for artificial bones to overcome bone damage due to osteoporosis by using calcium phosphate as a base material and perform chemical and surface engineering to increase the bioactivity of biomaterials | Biomaterial Design for Artificial Bone: Injectable Calcium Phosphate | Discovery learning
Cooperative learning Problem Based Learning |
Group discussion of bone cement requirements
Task: Bone cement design |
FF: 2 x 50
ST: 2 x 60 SS: 2 x 60 |
• Accuracy in designing biomaterials for artificial bone | 15 |
| 16 | Final exams | Written exam | 90 | The truth and completeness of the answer to the question | |||
| Total Rating | 100 | ||||||
Reference:
- Ratner, B.D., Hoffman, S. S., Schoen, F.J., and Lemons, J.E., 1996, Biomaterials science: introduction to Materials in medicine, Academic Press, San Diego
- Windarti, T, 2015, Buku Ajar: Biomaterial: Desain Tulang Artifisial
- Zhang, J., Liu, W., Schnitzler, V., Tancret, F., Bouler, J-M., 2014, Review: Calcium phosphate cements for bone substitution: chemistry, handling and mechanical properties, Acta Biomaterialia, 10, 1035-1049
Glossary
GLO = Graduate Learning Outcome
CLO = Course Learning Outcomes
FF = Face to Face Learning
ST = Structured tasks
SS = Self Study
